Researchers examined the outcomes of biochemical recurrence, incontinence and erectile dysfunction in 13,268 European men who had a radical prostatectomy, 443 of which were under age 50 years.
The study found than men younger than 50 were more likely to have low- risk, organ-confined and low-grade tumors (Gleason score ‹7). Also, the probability of biochemical-free survival at 2 and 5 years was high for men younger than 50.
Men under age 50 were less likely to have urinary incontinence after radical prostatectomy than men 50 and older. In recent years, continence rates were 97.4% for patients younger than 50 vs. 91.6% for patients 50 and older. Also, rates of post-operative erectile dysfunction were lower in men under 50 than in older patients. The study concluded that men younger than 50 diagnosed with localized prostate cancer should not be discouraged from having a radial prostatectomy.
Becker, A. et al. Functional and oncological outcomes of patients aged ‹50 years treated with radical prostatectomy for localised prostate cancer in a European population. BJU Int. 2014; 114(1):38-45.