Expansion of Cancer Risk Profile for BRCA1 and BRCA2 Pathogenic Variants

Categories: Spring 2023

It is well established that carriers of pathogenic BRCA mutations are at an increased risk in women for breast, ovarian, pancreatic cancer and melanoma, and in men, prostate, pancreatic, male breast cancer, and melanoma. To this group of cancers, a recent study from Japan that reviewed 63,828 patients and 37,086 controls found even more cancers that have an increased risk from these pathogenic variants, i.e.: biliary, esophageal, and gastric cancers.

JAMA Oncol 2022;8:871-878

 

 

RELATED QUEST ARTICLES

POPULAR QUEST ARTICLES

RECENT QUEST ARTICLES

Subscribe to Quest

"*" indicates required fields

Email*

This email address is only for subscribing or unsubscribing to or from Quest. Dr. Catalona cannot respond to questions concerning your Personal Health Information (PHI) that could identify you as an individual. This is a "cyber-security measure" for your protection that will help prevent anyone from legally or illegally accessing your personal health information.

Delivery Method (How do you want to receive your Quest publication?)*
Address*