Healthy lifestyle cuts prostate cancer mortality among high-risk men

Adherence to a healthy lifestyle is associated with close to a 50% lower risk for developing lethal prostate cancer among men at high risk for the disease according to a recent study.

The analysis included 12,411 genotyped men. The researchers found that the polygenic risk score enabled risk stratification not only for overall prostate cancer but also for lethal disease with a fourfold difference between men in the highest and lowest quartiles.  Adhering to a healthy lifestyle was associated with a decreased rate of lethal prostate cancer for men in the highest polygenic risk score quartile compared with having an unhealthy lifestyle.  There was no association seen between adhering to a healthy lifestyle and decreased risk for overall prostate cancer.

Lifestyle modifications, early screening, and early treatment may help combat high genetic risks in patients.

Health Day News. 2022, Jul 17.