Maximum tumor diameter provides information before treatment

Maximum tumor diameter on pretreatment MRI has the potential to provide further information to men with prostate cancer before definitive treatment.

This retrospective analysis included a cohort of 631 patients. Analysis identified 4 prognostic groups for patients treated with radical prostatectomy (RP), and 2 prognostic groups in those treated with radiotherapy. In the RP cohort, low/intermediate risk group patients with maximum tumor diameter 15 mm or more had significantly worse progression-free survival than those with maximum tumor diameter less than 14 mm. High-risk patients with radiographic extracapsular tumor extension had significantly worse progression-free survival than those without extracapsular extension. In the radical prostatectomy cohort, progression-free survival was significantly worse in the cohort with maximum tumor dimension 23 mm or more than those less than 23 mm.

Radiographic maximum tumor diameter may be a useful tool for patients with local/regional prostate cancer.