QUEST informs readers of the latest advances in urologic prostate cancer research, especially detection, prevention, and treatment.
Before performing complex operations such as robotic-assisted radical prostatectomy, surgeons review 2-dimensional MRI cross-sectional images to understand 3-dimentional (3D) patient-specific anatomy. This study utilized 3D virtual reality models for operative planning. Three-dimensional virtual reality planning supplemented information from MRI and…
This phase 2 trial was conducted across 41 urological oncology sites in 11 countries in Europe and North America. Eligible patients had metastatic castration-resistant prostate cancer and had previously received chemotherapy with docetaxel and up to one additional line of…
The search for improved prostate biopsy to diagnose prostate cancer began in earnest in the 1980’s. Multiparametric prostate MRI (mpMRI) fusion biopsy is widely employed and is currently considered the best technology to identify and target abnormalities that may harbor…
Personalized genomic classifiers have transformed the management of prostate cancer by identifying the most aggressive subsets of prostate cancer. However, to date, the performance of genomic classifiers to risk-classify African American men has been lacking. This study of the Decipher…
Dear Readers of Quest, As my wife, Jan, and I ring out the tempestuous 2022 and, hopefully, ring in a more peaceful, joyous, and prosperous year to come, I wish to express my deepest and sincerest appreciation for wonderful support…
BRCA Carriers More Likely to Develop Prostate Cancer New Foundation Launched to Discover Better Ways to Prevent, Detect, and Treat BRCA Related Cancers BRCA1 and BRCA2 are genes that produce proteins that help repair damaged DNA. Everyone has two copies…
Dr. Jeffrey S. Berger, MD, MS writes for JAMA (April 26, 2022) that it may be time to rethink the approach that had been accepted over the past decades of relying on aspirin in the primary prevention of cardiovascular disease…
The American Association of Genitourinary Surgeons is the oldest professional society in organized urology, being founded in 1886. Dr. Catalona is a past recipient of its honorary Barringer and Keys medals. He presented a research paper on prostate cancer genetics, moderated a…
BRCA1 and BRCA2 were identified in the 1990s as the causative genes underlying hereditary breast and ovarian cancer syndrome with genetic testing beginning during the same decade for treatment of patients and their relatives. The target BRCA1 and BRCA 2…
This issue of Quest features our Secretary-Treasurer, Jim Rothkopf, who has lived on the East Coast his entire life. Born in Brooklyn, he attended New York University for his undergraduate degree and received his M.B.A. degree from the American University…
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