QUEST informs readers of the latest advances in urologic prostate cancer research, especially detection, prevention, and treatment.
In this phase II trial, the authors investigated the efficacy of prostate-specific membrane antigen (PSMA)-radioguided surgery in identifying lymph node invasion during robot-assisted radical prostatectomy in patients with clinically-localized prostate cancer. Overall, 12 patients with intermediate-or high-risk prostate cancer underwent…
Black men have higher prostate cancer incidence and mortality than non-Hispanic white men. However, Black men have been underrepresented in clinical trials of PSA screening; therefore, there is a lack of data to guide screening recommendations for this population. The…
Before performing complex operations such as robotic-assisted radical prostatectomy, surgeons review 2-dimensional MRI cross-sectional images to understand 3-dimentional (3D) patient-specific anatomy. This study utilized 3D virtual reality models for operative planning. Three-dimensional virtual reality planning supplemented information from MRI and…
This phase 2 trial was conducted across 41 urological oncology sites in 11 countries in Europe and North America. Eligible patients had metastatic castration-resistant prostate cancer and had previously received chemotherapy with docetaxel and up to one additional line of…
The search for improved prostate biopsy to diagnose prostate cancer began in earnest in the 1980’s. Multiparametric prostate MRI (mpMRI) fusion biopsy is widely employed and is currently considered the best technology to identify and target abnormalities that may harbor…
Personalized genomic classifiers have transformed the management of prostate cancer by identifying the most aggressive subsets of prostate cancer. However, to date, the performance of genomic classifiers to risk-classify African American men has been lacking. This study of the Decipher…
Dear Readers of Quest, As my wife, Jan, and I ring out the tempestuous 2022 and, hopefully, ring in a more peaceful, joyous, and prosperous year to come, I wish to express my deepest and sincerest appreciation for wonderful support…
BRCA Carriers More Likely to Develop Prostate Cancer New Foundation Launched to Discover Better Ways to Prevent, Detect, and Treat BRCA Related Cancers BRCA1 and BRCA2 are genes that produce proteins that help repair damaged DNA. Everyone has two copies…
Dr. Jeffrey S. Berger, MD, MS writes for JAMA (April 26, 2022) that it may be time to rethink the approach that had been accepted over the past decades of relying on aspirin in the primary prevention of cardiovascular disease…
The American Association of Genitourinary Surgeons is the oldest professional society in organized urology, being founded in 1886. Dr. Catalona is a past recipient of its honorary Barringer and Keys medals. He presented a research paper on prostate cancer genetics, moderated a…
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