QUEST informs readers of the latest advances in urologic prostate cancer research, especially detection, prevention, and treatment.
The medications scrutinized in the study are 5-⍺ reductase inhibitors (5-ARIs), hormone blocking drugs frequently prescribed to treat benign prostatic hyperplasia (BPH) and male pattern baldness. The generic names are finasteride and dutasteride; the trade names include Proscar, Propecia, and…
In September, the U.S. Food and Drug Administration approved the drug apalutamide for the treatment of metastatic hormone-sensitive prostate cancer. Apalutamide is an oral drug in a class of medications called androgen receptor inhibitors. Androgens are male reproductive hormones that…
Tumors have unique genomic signatures based on their genetic makeup, and this genetic makeup can affect how well the cancer will respond to hormone therapy. Recently, a research team developed a genomic test that may help predict which patients with…
For the first time, prostate cancer has been treated based on the genetic makeup of the cancer, resulting in delayed disease progression, delayed time to pain progression, and potentially extending lives in patients with advanced, metastatic prostate cancer, according to…
After a patient’s biopsy, a pathologist examines the tissue specimen to see whether any abnormal growth is benign or malignant. However, errors in identifying the tissue’s characteristics can occur. A current area of scientific exploration concerns whether using new technologies,…
In addition to routine PSA screening, recent research has identified and is currently assessing numerous other strategies and tools available for the early detection of prostate cancer. Baseline PSA testing A midlife baseline PSA test can be used to guide…
Sir Winston Churchill said, “Never give up on something you can’t go a day without thinking about.” This resonates with me, as not a day goes by that I don’t think about many people with cancer. If you or a…
Who is at risk for low testosterone, and why is it important for men to be aware of testosterone deficiency? Testosterone deficiency, or hypogonadism, is an important condition for men to be aware of, because it can impair men’s health…
Andrew and Susan Fox with the Flying Scotsman train in Edinburgh, Scotland. They call themselves “train people.” Andrew Fox credits the railroad with many good things in his life: childhood joy, a fulfilling career, and the best way to travel…
Research continues to review details of PSA testing. Understanding the historical context, and the impact of screening, helps determine the best ways to use the test in a modern clinical setting. ©Dan Oldfield In 1992 – before the advent of…
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