QUEST informs readers of the latest advances in urologic prostate cancer research, especially detection, prevention, and treatment.
In the midst of the debate over PSA testing, the new National Comprehensive Cancer Network (NCCN) Guidelines for Prostate Cancer Early Detection aim to maximize the benefits and minimize the harms of PSA testing. These guidelines are important because many…
The Spring 2014 issue of QUEST reported that the FDA is reviewing the risk of stroke, heart attack and death in men taking testosterone products. The review was prompted by the publication of two studies that linked testosterone therapy and…
Dan Murphy ran in the 118th Boston Marathon only 15 months after having a radical prostatectomy. From start to finish, Murphy refused to let prostate cancer be a hurdle in his path. Murphy has been a dedicated runner since 1978….
Active surveillance (AS) is a management option for patients with favorable-risk prostate cancer. Drs. Stacy Loeb, M.D., of New York University, Pär Stattin, from the National Prostate Cancer Register of Sweden, and their colleagues reported on data from 11,726 men…
Researchers examined the outcomes of biochemical recurrence, incontinence and erectile dysfunction in 13,268 European men who had a radical prostatectomy, 443 of which were under age 50 years. The study found than men younger than 50 were more likely to…
The current standard of care is for men with metastatic prostate cancer to begin with androgen-deprivation therapy (ADT), also known as hormone therapy, then progress to chemotherapy after ADT has stopped working. Previous clinical trials have shown that this increases…
“The goals of radical prostatectomy are to prevent suffering and death from prostate cancer. This study provides new level-1 evidence that in low-risk patients, surgery significantly reduces suffering in those men who are otherwise healthy and have a long life…
Her two younger sisters were 9 and 15 years old. Their father’s diagnosis and treatment affected the entire Purze family, and they relied on each other for emotional support. “When my family was coping with my dad’s cancer, I learned…
Prostate cancer research has produced many new drugs, treatments, and biomarkers that are available to patients today, and many others are in the pipeline. I believe that the genetic revolution will usher in a new era of prostate cancer management…
However, prostate cancer cells can develop resistance to conventional hormonal therapy. This condition is called metastatic castration-resistant prostate cancer. New treatments are becoming available for this condition. Radium-223 Trial a Success Researchers reported favorable results from a phase 3 study…
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