QUEST informs readers of the latest advances in urologic prostate cancer research, especially detection, prevention, and treatment.
Researchers conducted a meta- analysis of ten genome-wide association studies of more than19,000 cases and 60,000 controls of African ancestry to identify common genetic variants contributing to the risk of prostate cancer in men of African ancestry. They discovered…
Grade group 1 (GG1) prostate cancers, with a Gleason score of 6, are considered low-risk and not likely to lead to death. Because they are generally slow-growing and not aggressive, treatment is often not needed. These cancers rarely spread to…
This study examined the use of PSMA-PET, an advanced imaging technique, and how its use might improve outcomes for patients with recurring prostate cancer. PSMA-PET is more sensitive and specific than older imaging methods like CT scans and bone…
Researchers compared the cardiovascular risks associated with luteinizing hormone-releasing hormone (LHRH) agonists versus gonadotropin-releasing hormone (GnRH) antagonists in prostate cancer patients undergoing androgen deprivation therapy (ADT). Scientists conducted a retrospective analysis using real-world data from more than 45,000 men with…
This study focused on men with prostate cancer who were at high risk for recurrence. Specifically, the researchers were interested in patients whose prostate-specific antigen (PSA) levels were rising quickly. When PSA levels double quickly, there is a higher risk…
This phase II clinical trial (ARTO trial) examined whether adding stereotactic body radiation therapy (SBRT) to a standard treatment of abiraterone acetate and prednisone (AAP) would help improve outcomes for patients with oligometastatic, castrate- resistant prostate cancer (CRPC). Oligometastatic CRPC…
Researchers sought to determine which factors lead to a shorter time to PSA failure, which is a sign of prostate cancer worsening. Their goal was to identify patients who may need more aggressive treatments and to test specified treatments…
As 2024 drew to a close, I attended the 101st annual meeting of the Clinical Society of Genitourinary Surgeons held at Stanford University. Doctor Carolyn Bertozzi, a guest speaker at the conference and the subject of our Feature QUEST article,…
Kenneth Carwell has lived within a 1-mile area his whole life, but his sphere of influence extends far beyond geographic boundaries. Ken’s educational training is in social work, and his roles and responsibilities throughout his 40-year career focused on…
Is equal access to health care associated with reduced racial and ethnic disparities in outcomes of nonmetastatic castration-resistant prostate cancer? A retrospective cohort study of approximately 13,000 veterans treated in an equal-access healthcare setting was conducted. Patients included in the…
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