QUEST informs readers of the latest advances in urologic prostate cancer research, especially detection, prevention, and treatment.
A recent phase II trial compared two treatments for advanced prostate cancer. One treatment used lutetium-177 [177Lu] Lu-PSMA- 617, and the other used cabazitaxel. Both treatments were given to men whose cancer had spread after receiving docetaxel. The study looked…
This retrospective, international study examined the safety and antitumor activity in 488 patients who had received previous treatment including docetaxel, cabazitaxel, abiraterone, and enzalutamide, lutetium-177 PSMA, and radium-223 dichloride. A decline in PSA was noted in 73% of patients, with…
Many cancer patients and their family members are encouraged to undergo germline genomic testing to evaluate the risk for cancer among their family members. Genomic sequencing has identified many rare, novel DNA variants in diverse populations. To determine whether a…
Cancer genomes from Black patients have been poorly studied. A Memorial Sloan Kettering Cancer Center study examining deep genomic sequencing of 333,908 tumor samples (including breast, colorectal, non-small cell lung, pancreatic, or prostate tumors) and 64,173 paired tumor-normal samples, including…
A study recently published in Cancer found that a greater consumption of plant-based foods is associated with higher quality of life. Stacy Loeb, M.D., Ph.D., and colleagues studied the relationship between plant-based diet indices after prostate cancer diagnosis and…
A new treatment called low- intensity shockwave therapy is being promoted for erectile dysfunction in the US. This therapy, similar to that used for kidney stones, is not approved by the FDA for this use. The usual treatments for…
Recommendation by urologist was the strongest determinate for AS decision. More than half of newly diagnosed patients with low-risk prostate cancer chose active surveillance (AS) with the recommendation from a urologist being the strongest determinant, according to a recent study…
A systematic review and meta-analysis This study investigated the impact of exercise on the quality of life (QoL) and metabolic health in men diagnosed with prostate cancer. The study, which included 33 randomized controlled trials with 2567 participants, found that…
Dr. Catalona conceived the Prostate Cancer Active Surveillance Project (PCASP) in 2016, shortly after the American Urological Association (AUA) launched its AQUA Registry to assist urologists in complying with the federal government’s requirement for physicians to report their outcomes…
Implementation science, a burgeoning field in public health research is the study of methods to promote the adoption and integration of evidence- based best practices, interventions, and policies into routine healthcare and public health settings to improve health in the…
"*" indicates required fields
