QUEST informs readers of the latest advances in urologic prostate cancer research, especially detection, prevention, and treatment.
Background: Many pathologists who examine prostate cancer biopsies believe that perineural invasion* (PNI) is present in all radical prostatectomy specimens if a careful search is made. For this reason, some pathologists do not even report the presence or absence of…
(This article is a summary prepared by Cecilia Lacks, PhD, for Quest readers of a Journal Article published in Nature Genetics, 2007, High-throughput Oncogene Mutation Profiling in Human Cancer. Its research and findings are a collaboration of over 50…
The genetic research of Dr. Catalona and his collaborators has contributed to significant findings in the genetics of prostate cancer: EGR-1 and TRMPSS2 One finding with extraordinary potential is a gene identified as EGR-1 that is up-regulated in prostate cancer….
Watchful Waiting: Seldom a Good Treatment Option I’m the Secretary of the URF Board and a patient of Dr. Catalona. He performed my radical prostatectomy in September 1997. I’ve written in QUEST for 5 years. I study and write and…
(reprinted courtesy of National Prostate Cancer Coalition) Prostate cancer death rates dropped 32.5 percent in 10 years, according to new reports, possibly as a result of a dramatic increase in early detection. The mortality rate for African American men is…
“Prostate cancer is not an old man’s disease.” Bob Buhle, single and not dating anyone, was diagnosed with prostate cancer in 2003 at age 39. One week after his surgery, Buhle met his wife to be, Heidi. And on October…
This information is an adapted version of a medical journal article written by William J. Catalona, MD; Misop Han, MD; and Stacy Loeb, MD. Should Screening for Prostate Cancer Begin Before 50 years old? We, as well as the National…
MedWire – ASCO Prostate Cancer Symposium (San Francisco, CA, USA) – February 24, 2006: The pros and cons of widespread PSA screening are constantly debated at medical meetings, and clinicians are still divided on whether or not it can reduced…
May 12, 2006 If lost in the wilderness, search and rescue experts will tell you the first rule is to stay put and do nothing. Help will find you. Not true for prostate cancer. And with good reason, prostate cancer…
A small but vocal group of physicians is saying that prostate cancer screening has resulted in overdiagnosis and therefore overtreatment of prostate cancers. The reality is that prostate cancer screening is doing considerably more good than harm. (Catalona and Graif,…
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