QUEST informs readers of the latest advances in urologic prostate cancer research, especially detection, prevention, and treatment.
Andrew Fox’s lifetime love affair with trains has provided him with a vocation, an avocation, and plenty of adventures. Andrew grew up in northern California and from an early age was fascinated by trains. He got his first job…
A recent study reported differences in the use of novel hormonal therapy (NHT) among Medicare beneficiaries with advanced prostate cancer (PC) based on their race. Researchers studied how NHT was used among men diagnosed with advanced PC between January 1,…
New study results found that Cabozantinib plus Atezolizumab (C+A) can significantly improve prognoses of patients with metastatic castration-resistant prostate cancer (mCRPC) that has progressed with prior novel hormonal therapy. This phase 3 study, found that patients in the C+A…
In this phase III trial, researchers compared treatments for patients with recurring prostate cancer. They looked at using hormone therapy alone, hormone therapy with apalutamide, or hormone therapy with abiraterone/prednisone and apalutamide. Patients had previously had surgery and had a…
(de novo is a phrase from Latin describing some biological process that has begun again) During a period with improvements in the treatment of advanced prostate cancer, there was a simultaneous clinically meaningful increase in mean survival for men with…
A recent phase II trial compared two treatments for advanced prostate cancer. One treatment used lutetium-177 [177Lu] Lu-PSMA- 617, and the other used cabazitaxel. Both treatments were given to men whose cancer had spread after receiving docetaxel. The study looked…
This retrospective, international study examined the safety and antitumor activity in 488 patients who had received previous treatment including docetaxel, cabazitaxel, abiraterone, and enzalutamide, lutetium-177 PSMA, and radium-223 dichloride. A decline in PSA was noted in 73% of patients, with…
Many cancer patients and their family members are encouraged to undergo germline genomic testing to evaluate the risk for cancer among their family members. Genomic sequencing has identified many rare, novel DNA variants in diverse populations. To determine whether a…
Cancer genomes from Black patients have been poorly studied. A Memorial Sloan Kettering Cancer Center study examining deep genomic sequencing of 333,908 tumor samples (including breast, colorectal, non-small cell lung, pancreatic, or prostate tumors) and 64,173 paired tumor-normal samples, including…
A study recently published in Cancer found that a greater consumption of plant-based foods is associated with higher quality of life. Stacy Loeb, M.D., Ph.D., and colleagues studied the relationship between plant-based diet indices after prostate cancer diagnosis and…
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