QUEST informs readers of the latest advances in urologic prostate cancer research, especially detection, prevention, and treatment.
Talazoparib is a drug in the class called “PARP inhibitors” that have been shown to be effective in treating advanced cancers, particularly in carriers of BRCA and other DNA repair genetic variants. Enzalutamide is a second-generation form of hormonal therapy…
The Benjamin Stockwell Barringer Medal was first offered in 1953 by Mrs. Barringer in memory of her late husband, the originator of the trans-perineal radioactive seed implant for prostate cancer. The medal is to be presented periodically to a…
Higher adherence to a plant-based diet is associated with a lower risk for prostate cancer progression and recurrence. As part of the Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE), researchers from the University of California, San Francisco analyzed…
Dairy foods, calcium intake, and risk of incident prostate cancer A prospective cohort study of 28,737 men who completed food frequency questionnaires and then were followed for cancer incidence by tracking them in cancer registries compared men in the bottom…
The incidence of prostate cancer is continually increasing. Black men are disproportionately affected by prostate cancer; they have the highest prostate cancer incidence in the United States with earlier presentation, more aggressive disease, and higher mortality rates versus White men….
It is well established that carriers of pathogenic BRCA mutations are at an increased risk in women for breast, ovarian, pancreatic cancer and melanoma, and in men, prostate, pancreatic, male breast cancer, and melanoma. To this group of cancers, a…
Prostate cancer is a major public health problem causing considerable side effects, suffering, death, and healthcare costs. The early treatment of clinically localized disease decreases prostate cancer deaths, but over-treatment of all early-stage patients results in unnecessary adverse side effects…
More of the prostate cancer deaths occurred in men initially diagnosed with Gleason 6 (low-grade) than in those diagnosed with Gleason 7 (high-grade). Prostate cancer is sometimes portrayed as a “toothless tiger,” and it is said that “Every man will…
2023 National Comprehensive Cancer Center Network Guidelines Dr. Catalona is a member of the National Comprehensive Cancer Center Network (NCCN) Early Prostate Cancer Detection Guideline Panel. In a recent article on which Dr. Catalona is a co- author, the…
Local therapies using stereotactic ablative radiation (SABR) are increasingly being used to treat patients with oligometastatic disease (only a few metastases) due to the accumulating evidence regarding its efficacy in improving oncologic outcomes. In patients with prostate cancer, there is…
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