QUEST informs readers of the latest advances in urologic prostate cancer research, especially detection, prevention, and treatment.
A review and analysis examined the use of second-generation antiandrogens (AAs) for treating prostate cancer and their potential cognitive and functional side effects. These AAs, including abiraterone, apalutamide, darolutamide, and enzalutamide, are becoming more frequently used in treatment. The researchers…
As we enter the end-of-year holiday season, I think of the many people with cancer and their families I encounter in my daily activities. I am happy to report that increasingly more patients are having their lives extended and their…
B.J. Rimel, MD is a gynecologic oncologist who by dint of her abiding interest and hard work is the Medical Director of the Cancer Clinical Trials Office at Cedars Sinai Medical Center in Los Angeles, one of the top-ranked hospitals…
The overall cancer mortality rate in the U.S. has decreased continuously since 1991, resulting in an overall drop of 33%: approximately 3.8 million cancer deaths averted. This progress is due to the uptake of screening for breast, colorectal, and prostate cancers….
Every 18 minutes a Black man is diagnosed with prostate cancer – the second leading cause of cancer death in Black men. In 2022, approximately 41,600 Black men were diagnosed that accounted for 37% of all new cancers among Black…
The living, learning, working, and playing conditions that affect a person’s health and quality of life are known as social determinants of health (SDOH). The study highlights the need to address racial disparities in healthcare and the importance of understanding…
This study examines how important it is for Black men to have access to trustworthy information about prostate cancer – a disease that disproportionately affects them. Black men are not well represented in online content about prostate cancer that many…
When diagnosed with localized prostate cancer, patients have three traditional options: active surveillance, surgery, or radiation therapy. Active surveillance involves closely monitoring the cancer without immediate treatment, radiation therapy uses radiation to kill the cancer while leaving the prostate in…
In the U.S., fewer men have been undergoing PSA screening since 2008, (largely due to the U.S. Preventive Services Task Force (USPSTF) revision of national guidelines. In 2008, the USPSTF recommended against screening men older than 75 years of age….
The International Society of Urologic Pathology (ISUP) 2019 modification of the prostate cancer grading system is now well-established for diagnosing and managing prostate cancer patients. Recently, some authors have called for removing the cancer label from Gleason grade group 1…
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