QUEST informs readers of the latest advances in urologic prostate cancer research, especially detection, prevention, and treatment.

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Effects of Metformin and statins on the outcomes in men with mCRPC

This retrospective analysis investigated whether the use of metformin and statins improve the overall survival and PSA response rate in men receiving abiraterone acetate plus prednisone/prednisolone (AAP) for metastatic castration-resistant prostate cancer (mCRPC) either before or after chemotherapy. The use…

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Multiethnic polygenic risk score model for prostate cancer risk

Polygenic risk scores (PRS) of common genetic variants have shown promise in prostate cancer risk stratification, but their validity across different ethnic populations has yet to be confirmed. These researchers evaluated a multiethnic polygenic risk score model based on 269 germline genetic…

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Vitamins and supplements not supported for most Americans

Kristin Samuelson of Northwestern University, wrote an article entitled “Vitamins, supplements are a ‘waste of money’ for most Americans.” There is a lot of money spent by Americans on multivitamins and dietary supplements-close to $50 billion in 2021. This article…

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Dr. Catalona recipient of NAIF Chamber of Commerce Award

The Italian American Chamber of Commerce Midwest is proud to present the 2022 Excellence Award to William Catalona, MD, Professor of Urology, Northwestern University, for his outstanding achievements and contributions.  Previous award recipients include Riccardo Muti, Director, Chicago Symphony Orchestra,…

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New prostate cancer treatment approved by FDA

A targeted radioligand therapy, Pluvicto (lutetium LU 177 vipivotide tetraxetan), has been approved for use in patients with previously treated metastatic castration-resistant prostate cancer (mCRPC). Eligible patients must have been treated previously with taxane-based chemotherapy and androgen deprivation therapy, and…

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